Skip to main content
SpringerLink
Log in

PLANT IMMUNITY

Deceiving the chaperone

  • News & Views
  • Published:

From Nature Plants

View current issue Submit your manuscript

Heat-shock protein 90 (HSP90) chaperones play an essential role in plant defence by assisting the folding of client proteins needed for immunity. A newly identified bacterial effector promotes disease by mimicking a HSP90 client, functioning as a minimal kinase that phosphorylates and inactivates the chaperone.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: A schematic model on the disruption of HSP90’s function in plant defence by the bacterial type III effector HopBF1.

References

  1. Weinhold, A. R. Annu. Rev. Phytopathol. 34, 1–11 (1996).

    Article  CAS  Google Scholar 

  2. Jones, J. D. & Dangl, J. L. Nature 444, 323–329 (2006).

    Article  CAS  Google Scholar 

  3. Toruno, T. Y., Stergiopoulos, I. & Coaker, G. Annu. Rev. Phytopathol. 54, 419–441 (2016).

    Article  CAS  Google Scholar 

  4. Lopez, V. A. et al. Cell 179, 205–218 (2019).

    Article  CAS  Google Scholar 

  5. Mayor, A., Martinon, F., De Smedt, T., Petrilli, V. & Tschopp, J. Nat. Immunol. 8, 497–503 (2007).

    Article  CAS  Google Scholar 

  6. Martine, P. & Rébé, C. Int. J. Mol. Sci. 20, 4508 (2019).

    Article  Google Scholar 

  7. Shirasu, K. Annu. Rev. Plant Biol. 60, 139–164 (2009).

    Article  CAS  Google Scholar 

  8. Wu, L., Chen, H., Curtis, C. & Fu, Z. Q. Virulence 5, 710–721 (2014).

    Article  CAS  Google Scholar 

  9. Schopf, F. H., Biebl, M. M. & Buchner, J. Nat. Rev. Mol. Cell Bio. 18, 345–360 (2017).

    Article  CAS  Google Scholar 

  10. Rowlands, M. et al. J. Biomol. Screen. 15, 279–286 (2010).

    Article  CAS  Google Scholar 

  11. Cui, H. et al. Cell Host Microbe 7, 164–175 (2010).

    Article  CAS  Google Scholar 

  12. Wu, M. & Hardwidge, P. R. Pathogens 7, 87 (2018).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Plant Protection, Jiangsu Academy of Agricultural Sciences, Jiangsu Key Laboratory for Food Quality and Safety-State Key Laboratory Cultivation Base of Ministry of Science and Technology, Nanjing, China

    Huan Chen & Fengquan Liu

  2. Department of Biological Sciences, University of South Carolina, Columbia, SC, USA

    Huan Chen & Zheng Qing Fu

Authors
  1. Huan Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Fengquan Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zheng Qing Fu
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Fengquan Liu or Zheng Qing Fu.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Chen, H., Liu, F. & Fu, Z.Q. Deceiving the chaperone. Nat. Plants 5, 1110–1111 (2019). https://doi.org/10.1038/s41477-019-0552-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41477-019-0552-3

  • Springer Nature Limited

Search

Navigation