Pathogen perception triggers a monomeric nucleotide-binding leucine-rich plant immune receptor to form a pentameric wheel-like complex termed a resistosome, with the N-terminal α helices forming a funnel-shaped structure that may perturb plasma membrane integrity to cause hypersensitive cell death.
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Adachi, H., Kamoun, S. & Maqbool, A. A resistosome-activated ‘death switch’. Nat. Plants 5, 457–458 (2019). https://doi.org/10.1038/s41477-019-0425-9
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DOI: https://doi.org/10.1038/s41477-019-0425-9
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