Skip to main content
SpringerLink
Log in

PROTEIN EVOLUTION

Tinker, tailor, soldier, enzyme

  • News & Views
  • Published:

From Nature Plants

View current issue Submit your manuscript

Enzymes are a great example of the tight link between sequence, structure and function. A recent study of two dehydrogenases shows exactly how small changes in sequence can have great impacts on function.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1: Enzymes and enzyme families are hubs for function and regulation.

References

  1. Schenck, C.  A. et al. Nat. Chem. Biol. 13, 1029–1035 (2017).

    Article  CAS  PubMed  Google Scholar 

  2. El-Azaz, J., de la Torre, F., Ávila, C. & Cánovas, F. M. Plant J. 87, 215–229 (2016).

    Article  CAS  PubMed  Google Scholar 

  3. Mendonça, L. M. F. & Marana, S. R. Biochim. Biophys. Acta 1814, 1616–1623 (2011).

    Article  PubMed  Google Scholar 

  4. Huang, J. et al. Plant Physiol. 153, 1526–1538 (2010).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Jeffery, C. J. in Molecular Chaperones and Cell Signalling (eds Henderson, B. & Pockley, A. G.) 61–77 (Cambridge Univ. Press, Cambridge, 2005).

  6. Jeffery, C. J. J. Proteom. 134, 19–24 (2016).

    Article  CAS  Google Scholar 

  7. Braun, P. & Gingras, A.-C. Proteomics 12, 1478–1498 (2012).

    Article  CAS  PubMed  Google Scholar 

  8. Jacob, F. Science 196, 1161–1166 (1977).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biology, Western University, London, Ontario, Canada

    Susanne E. Kohalmi & Emily J. Clayton

Authors
  1. Susanne E. Kohalmi
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Emily J. Clayton
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Susanne E. Kohalmi.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Kohalmi, S.E., Clayton, E.J. Tinker, tailor, soldier, enzyme. Nature Plants 3, 848–849 (2017). https://doi.org/10.1038/s41477-017-0047-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41477-017-0047-z

  • Springer Nature Limited

Search

Navigation