Skip to main content

Advertisement

Log in

Revealing the diversity of neutrophil functions and subsets

  • Research Highlight
  • Published:
Cellular & Molecular Immunology Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

References

  1. Yang, W. et al. Neutrophils promote the development of reparative macrophages mediated by ROS to orchestrate liver repair. Nat. Commun. 10, 1076 (2019).

    Article  Google Scholar 

  2. Ballesteros, I. et al. Co-option of neutrophil fates by tissue environments. Cell 183, 1282–1297.e18 (2020).

    Article  CAS  Google Scholar 

  3. Sas, A. R. et al. A new neutrophil subset promotes CNS neuron survival and axon regeneration. Nat. Immunol. 21, 1496–1505 (2020).

    Article  Google Scholar 

  4. Soehnlein, O. & Lindbom, L. Phagocyte partnership during the onset and resolution of inflammation. Nat. Rev. Immunol. 10, 427–439 (2010).

    Article  CAS  Google Scholar 

  5. Aurora, A. B. & Olson, E. N. Immune modulation of stem cells and regeneration. Cell Stem Cell 15, 14–25 (2014).

    Article  CAS  Google Scholar 

  6. Lavin, Y. et al. Innate immune landscape in early lung adenocarcinoma by paired single-cell analyses. Cell 169, 750–765.e17 (2017).

    Article  CAS  Google Scholar 

  7. Blazquez-Prieto, J. et al. Impaired lung repair during neutropenia can be reverted by matrix metalloproteinase-9. Thorax 73, 321–330 (2018).

    Article  Google Scholar 

  8. Fridlender, Z. G. et al. Polarization of tumor-associated neutrophil phenotype by TGF-beta: “N1” versus “N2” TAN. Cancer Cell 16, 183–194 (2009).

    Article  CAS  Google Scholar 

  9. Giles, D. A. et al. Myeloid cell plasticity in the evolution of central nervous system autoimmunity. Ann. Neurol. 83, 131–141 (2018).

    Article  CAS  Google Scholar 

  10. Jassam, Y. N. et al. Neuroimmunology of traumatic brain injury: time for a paradigm shift. Neuron 95, 1246–1265 (2017).

    Article  CAS  Google Scholar 

Download references

Acknowledgements

We thank Angela Morben, DVM, ELS, from Edanz Group (https://en-author-services.edanz.com/ac) for editing the English text of a draft of this manuscript. This work was supported by AMED (grant number JP20fk0108129), GSK (grant number A-32), and the Japan Intractable Diseases (Nanbyo) Research Foundation (grant number 2020B02).

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Hiroshi Kida.

Ethics declarations

Competing interests

The authors declare no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fukushima, K., Nabeshima, H. & Kida, H. Revealing the diversity of neutrophil functions and subsets. Cell Mol Immunol 18, 781–783 (2021). https://doi.org/10.1038/s41423-021-00638-3

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41423-021-00638-3

  • Springer Nature Limited

Navigation