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En masse discovery of anti-cancer human monoclonal antibodies by de novo assembly of immunoglobulin sequences from transcriptomes and genome sequences of cancer tissues

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Acknowledgements

Part of the study was performed when the authors were at the Children’s National Medical Center.

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Author notes

  1. These authors contributed equally: Peng Zhang, Hung-Yen Chou

Authors and Affiliations

  1. Division of Immunotherapy, Institute of Human Virology, University of Maryland School of Medicine, Baltimore, MD, 21201, USA

    Peng Zhang, Hung-Yen Chou, Pan Zheng & Yang Liu

  2. The Institute for Biomedical Sciences, The George Washington University, Washington, DC, 20037, USA

    Hung-Yen Chou

  3. Center for Cancer and Immunology Research, Children’s Research Institute, Children’s National Health System, Washington, DC, 20010, USA

    Lei Young

  4. OncoImmune, Inc, Rockville, MD, 20852, USA

    Pan Zheng & Yang Liu

Authors
  1. Peng Zhang
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  2. Hung-Yen Chou
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  3. Lei Young
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  4. Pan Zheng
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  5. Yang Liu
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Contributions

Pe.Z. and H.-Y.C. performed the experiments and analyzed the data. L.Y. helped with the experiments. Y.L. and Pa.Z. supervised the studies, designed the experiments and wrote the manuscript along with Pe.Z. and H.-Y.C.

Corresponding authors

Correspondence to Pan Zheng or Yang Liu.

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Competing interests

Y.L. and Pa.Z. are co-founders of and have equity interests in OncoImmune, Inc. The remaining authors declare no competing interests.

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Zhang, P., Chou, HY., Young, L. et al. En masse discovery of anti-cancer human monoclonal antibodies by de novo assembly of immunoglobulin sequences from transcriptomes and genome sequences of cancer tissues. Cell Mol Immunol 16, 943–945 (2019). https://doi.org/10.1038/s41423-019-0299-9

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  • DOI: https://doi.org/10.1038/s41423-019-0299-9

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