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Uracil-DNA glycosylase is not implicated in the choice of the DNA repair pathway during B-cell class switch recombination

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Acknowledgements

We thank Dr. Tomas Lindahl for sending us the UNG-deficient mice. This work was supported by ANR (projet EpiSwitch-3’RR 2016). N.G. was supported by a grant from the Association de Spécialisation et d’Orientation Scientifique (Lebanon) and the municipality of Khiam (Lebanon). H.I. is supported by CORC (FJA/NP 2015-109) and the University of Limoges. The authors are “Equipe Labellisée LIGUE 2018.” We thank the GénoLim platform and the Cytometry platform of the University of Limoges for sequencing and cell sorting. F.B. is supported by Fondation Partenariale de l’Université de Limoges and ALURAD.

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  1. These authors contributed equally: Nour Ghazzaui and Hussein Issaoui.

Authors and Affiliations

  1. UMR CNRS 7276, INSERM U1262, University of Limoges, CBRS, rue Pr. Descottes, 87025, Limoges, France

    Nour Ghazzaui, Hussein Issaoui, Yves Denizot & François Boyer

  2. INSERM U1236, Rennes 1 University, Rennes, France

    Alexis Saintamand

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  1. Nour Ghazzaui
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  2. Hussein Issaoui
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  3. Alexis Saintamand
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  4. Yves Denizot
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  5. François Boyer
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Contributions

Y.D. designed the research. N.G., H.I., and A.S. performed the research. A.S., F.B., and Y.D. analyzed the data. A.S., F.B., and Y.D. wrote the paper.

Corresponding author

Correspondence to Yves Denizot.

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The authors declare no competing interests.

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Ghazzaui, N., Issaoui, H., Saintamand, A. et al. Uracil-DNA glycosylase is not implicated in the choice of the DNA repair pathway during B-cell class switch recombination. Cell Mol Immunol 16, 93–95 (2019). https://doi.org/10.1038/s41423-018-0034-y

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  • DOI: https://doi.org/10.1038/s41423-018-0034-y

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