Abstract
Sociodemographic and lifestyle factors may play a role in determining whether patients with clinically localized prostate cancer (PC) are managed with active surveillance (AS), radical prostatectomy (RP), or radiation therapy (RT); however, these relationships have not been well examined. In a cross-sectional study conducted within an equal access healthcare system, multivariable adjusted regression analysis revealed that living with a spouse or partner was associated with a 65% lower chance of being managed by RT (P = 0.001) and 57% lower risk of being managed by AS (P = 0.042) compared with RP. No other sociodemographic or lifestyle factors were independently associated with treatment modality.
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EMA: Conceptualization, writing–original draft and writing–review and editing. LG: Formal analysis, writing–review, and editing. TO: Formal analysis, writing–review, and editing. AMDH: Methodology, data collection, writing–review, and editing. EW: Methodology, data collection, writing–review, and editing. CJG: Writing–review, and editing. DJL: Writing–review, and editing. TJD: Methodology, writing–review, and editing. SJF: Conceptualization, methodology, data collection, supervision, writing–review, and editing. ZSZ: Conceptualization, methodology, supervision, writing–original draft, and writing–review and editing. IC: Conceptualization, methodology, supervision, writing–original draft, and writing–review and editing.
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The authors have no conflicts of interest related to this work. ZSZ was on the external advisory board for the Scripps Proton Therapy Center and has consulted for EMD Serono. ZSZ’s spouse does legal work for Johnson and Johnson and Allergan through her law firm. All other authors have no disclosures.
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Anderson, E.M., Gu, L., Oyekunle, T. et al. Lifestyle and sociodemographic factors associated with treatment choice of clinically localized prostate cancer in an equal access healthcare system. Prostate Cancer Prostatic Dis 25, 593–595 (2022). https://doi.org/10.1038/s41391-022-00551-4
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DOI: https://doi.org/10.1038/s41391-022-00551-4
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