Skip to main content
Log in

Reply to: “NG2-glia: rising stars in stress-related mental disorders?”

  • Correspondence
  • Published:
Molecular Psychiatry Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Poggi G, Wennström M, Müller MB, Treccani G NG2-glia: rising stars in stress-related mental disorders? Mol Psychiatry. 2022 2022;1–3.

  2. Tanti A, Belliveau C, Nagy C, Maitra M, Denux F, Perlman K, et al. Child abuse associates with increased recruitment of perineuronal nets in the ventromedial prefrontal cortex: a possible implication of oligodendrocyte progenitor cells. Mol Psychiatry 2021 2021;1–10.

  3. Zhang X, Liu Y, Hong X, Li X, Meshul CK, Moore C, et al. NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety. Nat Commun. 2021;12:1–18.

    Google Scholar 

  4. Fang LP, Zhao N, Caudal LC, Chang HF, Zhao R, Lin CH, et al. Impaired bidirectional communication between interneurons and oligodendrocyte precursor cells affects social cognitive behavior. Nat Commun. 2022;13:1–14.

    Article  Google Scholar 

  5. Orduz D, Maldonado PP, Balia M, Vélez-Fort M, de Sars V, Yanagawa Y, et al. Interneurons and oligodendrocyte progenitors form a structured synaptic network in the developing neocortex. Elife. 2015;2015:1–53.

    Google Scholar 

  6. Serrano-Regal MP, Bayón-Cordero L, Ordaz RP, Garay E, Limon A, Arellano RO, et al. Expression and function of GABA receptors in myelinating cells. Front Cell Neurosci. 2020; 14. https://doi.org/10.3389/FNCEL.2020.00256.

  7. Devienne G, Picaud S, Cohen I, Piquet J, Tricoire L, Testa D, et al. Regulation of perineuronal nets in the adult cortex by the activity of the cortical network. J Neurosci. 2021;41:5779–90.

    Article  CAS  Google Scholar 

  8. Kohnke S, Buller S, Nuzzaci D, Ridley K, Lam B, Pivonkova H, et al. Nutritional regulation of oligodendrocyte differentiation regulates perineuronal net remodeling in the median eminence. Cell Rep 2021; 36. https://doi.org/10.1016/J.CELREP.2021.109362.

  9. Nagy C, Maitra M, Tanti A, Suderman M, Théroux JF, Davoli MA, et al. Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons. Nat Neurosci. 2020;23:771–81.

    Article  CAS  Google Scholar 

  10. Boulanger JJ, Messier C. Oligodendrocyte progenitor cells are paired with GABA neurons in the mouse dorsal cortex: Unbiased stereological analysis. Neuroscience. 2017;362:127–40.

    Article  CAS  Google Scholar 

  11. Treccani G, Schlegelmilch AL, Schultz N, Herzog DP, Bessa JM, Sotiropoulos I, et al. Hippocampal NG2+ pericytes in chronically stressed rats and depressed patients: a quantitative study. Stress. 2021;24:353–8.

    Article  CAS  Google Scholar 

  12. Spitzer SO, Sitnikov S, Kamen Y, Evans KA, Kronenberg-Versteeg D, Dietmann S, et al. Oligodendrocyte progenitor cells become regionally diverse and heterogeneous with age. Neuron. 2019;101:459–471.e5.

    Article  CAS  Google Scholar 

  13. Venturino A, Schulz R, De Jesús-Cortés H, Maes ME, Nagy B, Reilly-Andújar F, et al. Microglia enable mature perineuronal nets disassembly upon anesthetic ketamine exposure or 60-Hz light entrainment in the healthy brain. Cell Rep. 2021;36:109313.

    Article  CAS  Google Scholar 

  14. Pantazopoulos H, Gisabella B, Rexrode L, Benefield D, Yildiz E, Seltzer P, et al. Circadian rhythms of perineuronal net composition. eNeuro. 2020;7:1–21.

    Article  Google Scholar 

  15. Favuzzi E, Huang S, Saldi GA, Binan L, Ibrahim LA, Fernández-Otero M, et al. GABA-receptive microglia selectively sculpt developing inhibitory circuits. Cell. 2021;184:4048–4063.e32.

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Contributions

CB, NM, and AT prepared the manuscript, and all authors contributed to and approved its final version.

Corresponding authors

Correspondence to Naguib Mechawar or Arnaud Tanti.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Belliveau, C., Mechawar, N. & Tanti, A. Reply to: “NG2-glia: rising stars in stress-related mental disorders?”. Mol Psychiatry 28, 521–522 (2023). https://doi.org/10.1038/s41380-022-01889-w

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s41380-022-01889-w

  • Springer Nature Limited

Navigation