Skip to main content
SpringerLink
Log in

Of Fat flies and Hippos, or the magic of animal size

  • News & Views
  • Published:

From Nature Structural & Molecular Biology

View current issue Submit your manuscript

A stream of papers exposes the molecular nuts and bolts of a mechanism that prevents cells from becoming immortal.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: Schematic view of the Hpo pathway.

Katie Ris

References

  1. Xu, T., Wang, W., Zhang, S., Stewart, R.A. & Yu, W. Development 121, 1053–1063 (1995).

    CAS  Google Scholar 

  2. Justice, R.W., Zilian, O., Woods, D.F., Noll, M. & Bryant, P.J. Genes Dev. 9, 534–546 (1995).

    Article  CAS  Google Scholar 

  3. Tapon, N. et al. Cell 110, 467–478 (2002).

    Article  CAS  Google Scholar 

  4. Harvey, K.F., Pfleger, C.M. & Hariharan, I.K. Cell 114, 457–467 (2003).

    Article  CAS  Google Scholar 

  5. Wu, S., Huang, J., Dong, J. & Pan, D. Cell 114, 445–456 (2003).

    Article  CAS  Google Scholar 

  6. Huang, J., Wu, S., Barrera, J., Matthews, K. & Pan, D. Cell 122, 421–434 (2005).

    Article  CAS  Google Scholar 

  7. Lai, Z.C. et al. Cell 120, 675–685 (2005).

    Article  CAS  Google Scholar 

  8. Edgar, B.A. Cell 124, 267–273 (2006).

    Article  CAS  Google Scholar 

  9. Neufeld, T.P., de la Cruz, A.F., Johnston, L.A. & Edgar, B.A. Cell 93, 1183–1193 (1998).

    Article  CAS  Google Scholar 

  10. Willecke, M. et al. Curr. Biol. 16, 2090–2100 (2006).

    Article  CAS  Google Scholar 

  11. Bennett, F.C. & Harvey, K.F. Curr. Biol. 16, 2101–2110 (2006).

    Article  CAS  Google Scholar 

  12. Cho, E. et al. Nat. Genet. 38, 1142–1150 (2006).

    Article  CAS  Google Scholar 

  13. Colombani, J., Polesello, C., Josue, F. & Tapon, N. Curr. Biol. 16, 1453–1458 (2006).

    Article  CAS  Google Scholar 

  14. Hamaratoglu, F. et al. Nat. Cell Biol. 8, 27–36 (2006).

    Article  CAS  Google Scholar 

  15. Nolo, R., Morrison, C.M., Tao, C., Zhang, X. & Halder, G. Curr. Biol. 16, 1895–1904 (2006).

    Article  CAS  Google Scholar 

  16. Silva, E., Tsatskis, Y., Gardano, L., Tapon, N. & McNeill, H. Curr. Biol. 16, 2081–2089 (2006).

    Article  CAS  Google Scholar 

  17. Thompson, B.J. & Cohen, S.M. Cell 126, 767–774 (2006).

    Article  CAS  Google Scholar 

  18. McCartney, B.M., Kulikauskas, R.M., LaJeunesse, D.R. & Fehon, R.G. Development 127, 1315–1324 (2000).

    CAS  PubMed  Google Scholar 

  19. Bryant, P.J., Huettner, B., Held, L.I., Jr. Ryerse, J. & Szidonya, J. Dev. Biol. 129, 541–554 (1988).

    Article  CAS  Google Scholar 

  20. Mao, Y. et al. Development 133, 2539–2551 (2006).

    Article  CAS  Google Scholar 

  21. Zilian, O. et al. Development 126, 5409–5420 (1999).

    CAS  PubMed  Google Scholar 

  22. Matakatsu, H. & Blair, S.S. Development 133, 2315–2324 (2006).

    Article  CAS  Google Scholar 

  23. Matakatsu, H. & Blair, S.S. Development 131, 3785–3794 (2004).

    Article  CAS  Google Scholar 

  24. Cho, E. & Irvine, K.D. Development 131, 4489–4500 (2004).

    Article  CAS  Google Scholar 

  25. Strutt, H., Mundy, J., Hofstra, K. & Strutt, D. Development 131, 881–890 (2004).

    Article  CAS  Google Scholar 

  26. Brennecke, J., Hipfner, D.R., Stark, A., Russell, R.B. & Cohen, S.M. Cell 113, 25–36 (2003).

    Article  CAS  Google Scholar 

  27. Hipfner, D.R., Weigmann, K. & Cohen, S.M. Genetics 161, 1527–1537 (2002).

    CAS  PubMed  PubMed Central  Google Scholar 

  28. Raisin, S., Pantalacci, S., Breittmayer, J.P. & Leopold, P. Genetics 164, 1015–1025 (2003).

    CAS  PubMed  PubMed Central  Google Scholar 

  29. Mikeladze-Dvali, T. et al. Cell 122, 775–787 (2005).

    Article  CAS  Google Scholar 

  30. Blaumueller, C.M. & Mlodzik, M. Mech. Dev. 92, 251–262 (2000).

    Article  CAS  Google Scholar 

  31. Maitra, S., Kulikauskas, R.M., Gavilan, H. & Fehon, R.G. Curr. Biol. 16, 702–709 (2006).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. the Centro Andaluz de Biología del Desarrollo, Consejo Superior de Investigaciones Científicas-Universidad Pablo de Olavide, Seville, 41013, Spain

    Fernando Casares, Carlos M Luque & Maria J Tavares

Authors
  1. Fernando Casares
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Carlos M Luque
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Maria J Tavares
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Casares, F., Luque, C. & Tavares, M. Of Fat flies and Hippos, or the magic of animal size. Nat Struct Mol Biol 13, 1051–1053 (2006). https://doi.org/10.1038/nsmb1206-1051

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsmb1206-1051

  • Springer Nature America, Inc.

Search

Navigation