Two new studies show that a noncoding RNA, B2, acts as a novel regulator of transcription. This RNA interacts with the general transcription machinery, thereby inhibiting transcription during heat shock response in mice.
References
Eddy, S.R. Nat. Rev. Genet. 2, 919–929 (2001).
Moore, P.B. & Steitz, T.A. Annu. Rev. Biochem. 72, 813–850 (2003).
Bartel, D.P. Cell 116, 281–297 (2004).
Carrington, J.C. & Ambros, V. Science 301, 336–338 (2003).
Gottesman, S. Annu. Rev. Microbiol. 58, 303–328 (2004).
Storz, G., Opdyke, J.A. & Zhang, A. Curr. Opin. Microbiol. 4, 140–144 (2004).
Allen, T.A., Von Kaenel, S., Goodrich, J.A. & Kugel, J.F. Nat. Struct. Mol. Biol. 11, 816–821 (2004).
Espinoza, C.A., Allen, T.A., Hieb, A.R., Kugel, J.F. & Goodrich, J.A. Nat. Struct. Mol. Biol. 11, 822–829 (2004).
Weiner, A.M. Curr. Opin. Cell Biol. 14, 343–350 (2002).
Fornace, A.J. Jr. & Mitchell, J.B. Nucleic Acids Res. 14, 5793–5811 (1986).
Li, T.-H., Spearow, J., Rubin, C.M. & Schmid, C.W. Gene 239, 367–372 (1999).
Kugel, J.F. & Goodrich, J.A. Mol. Cell. Biol. 22, 762–773 (2002).
Wassarman, K.M. & Storz, G. Cell 101, 613–623 (2000).
Trotochaud, A.E. & Wassarman, K.M. J. Bacteriol. 186, 4978–4985 (2004).
Kwek, K.Y. et al. Nat. Struct. Biol. 11, 800–805 (2002).
Yang, Z., Zhu, Q., Luo, K. & Zhou, Q. Nature 414, 317–322 (2001).
Nguyen, V.T., Kiss, T., Michels, A.A. & Bensaude, O. Nature 414, 322–325 (2001).
Fong, Y.W. & Zhou, Q. Nature 414, 929–933 (2001).
Kuwabara, T., Hsieh, J., Nakashima, K., Taira, K. & Gage, F.H. Cell 116, 779–793 (2004).
Andersen, A.A. & Panning, B. Curr. Opin. Cell Biol. 15, 281–289 (2003).
Lanz, R.B. et al. Cell 97, 17–27 (1999).
Borukhov, S. & Nudler, E. Curr. Opin. Microbiol. 6, 93–100 (2003).
Hahn, S. Nat. Struct. Mol. Biol. 11, 394–403 (2004).
Young, B.A., Gruber, T.M. & Gross, C.A. Cell 109, 417–420 (2002).
Wassarman, K.M. Cell 109, 141–144 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Wassarman, K. RNA regulators of transcription. Nat Struct Mol Biol 11, 803–804 (2004). https://doi.org/10.1038/nsmb0904-803
Issue Date:
DOI: https://doi.org/10.1038/nsmb0904-803
- Springer Nature America, Inc.
This article is cited by
-
Transcriptional activation by bidirectional RNA polymerase II elongation over a silent promoter
EMBO reports (2005)
-
A non-starter
Nature Reviews Molecular Cell Biology (2004)