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Moving parts: how the adaptor protein CRK is regulated, and regulates

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The solution structures of multiple forms of the adaptor protein CRK show how its domains fit together, providing insight into the autoregulation and ligand-mediated regulation of CRK.

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Figure 1: Domain organization of CRK isoforms and constructs used in recent structural studies.

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Cowburn, D. Moving parts: how the adaptor protein CRK is regulated, and regulates. Nat Struct Mol Biol 14, 465–466 (2007). https://doi.org/10.1038/nsmb0607-465

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