Skip to main content
Log in

Taking Drosophila Rad51 for a SPiN

  • News & Views
  • Published:

From Nature Structural & Molecular Biology

View current issue Submit your manuscript

A recent paper reports that Spn-A is the Rad51 ortholog in Drosophila melanogaster. This and other findings in this study open the door to genetic analysis of Rad51 functions in a model metazoan.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Homologous recombination and the Rad51 family.

References

  1. Haber, J.E. Trends Genet. 16, 259–264 (2000).

    Article  CAS  Google Scholar 

  2. Sung, P., Krejci, L., Van Komen, S. & Sehorn, M.G. J. Biol. Chem. 278, 42729–42732 (2003).

    Article  CAS  Google Scholar 

  3. Symington, L.S. Micro. Mol. Biol. Rev. 66, 630–670 (2002).

    Article  CAS  Google Scholar 

  4. Tsuzuki, T. et al. Proc. Natl. Acad. Sci. USA 93, 6236–6240 (1996).

    Article  CAS  Google Scholar 

  5. McKee, B.D., Ren, X. & Hong, C.A. Chromosoma 104, 479–488 (1996).

    CAS  PubMed  Google Scholar 

  6. Akaboshi, E., Inoue, Y. & Ryo, H. Jap. J. Genet. 69, 663–670 (1994).

    Article  CAS  Google Scholar 

  7. Staeva-Vieira, E., Yoo, S. & Lehmann, R. EMBO J. 22, 5863–5874 (2003).

    Article  CAS  Google Scholar 

  8. Dobens, L.L. & Raftery, L.A. Dev. Dyn. 218, 80–93 (2000).

    Article  CAS  Google Scholar 

  9. Morris, J. & Lehmann, R. Curr. Biol. 9, R55–58 (1999).

    Article  CAS  Google Scholar 

  10. Ghabrial, A., Ray, R.P. & Schüpbach, T. Genes Dev. 12, 2711–2723 (1998).

    Article  CAS  Google Scholar 

  11. Abdu, U., Gonzalez-Reyes, A., Ghabrial, A. & Schupbach, T. Genetics 165, 197–204 (2003).

    CAS  PubMed  PubMed Central  Google Scholar 

  12. Thacker, J. Trends Genet. 15, 166–168 (1999).

    Article  CAS  Google Scholar 

  13. Masson, J.Y. & West, S.C. Trends Biochem. Sci. 26, 131–136 (2001).

    Article  CAS  Google Scholar 

  14. Sekelsky, J.J., Brodsky, M.H. & Burtis, K.C. J. Cell Biol. 150, F31–F36 (2000).

    Article  CAS  Google Scholar 

  15. Li, Z., Golub, E.I., Gupta, R. & Radding, C.M. Proc. Natl. Acad. Sci. USA 94, 11221–11226 (1997).

    Article  CAS  Google Scholar 

  16. Bishop, D.K., Park, D., Xu, L. & Kleckner, N. Cell 69, 439–456 (1992).

    Article  CAS  Google Scholar 

  17. Yoshida, K. et al. Mol. Cell 1, 707–718 (1998).

    Article  CAS  Google Scholar 

  18. Hunter, N. Mol. Cell 12, 533–535 (2003).

    Article  CAS  Google Scholar 

  19. Thompson, J.D., Gibson, T.J., Plewniak, F., Jeanmougin, F., & Higgins, D.G. Nucleic Acids Res. 25, 4876–4882 (1997).

    Article  CAS  Google Scholar 

  20. Page, R.D.M. Comp. Appl. Biosci. 12, 357–358 (1996).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Radford, S., Sekelsky, J. Taking Drosophila Rad51 for a SPiN. Nat Struct Mol Biol 11, 9–10 (2004). https://doi.org/10.1038/nsmb0104-9

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nsmb0104-9

  • Springer Nature America, Inc.

This article is cited by

Navigation