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Ribosome origami

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Assembly of the small ribosomal subunit from an RNA strand and 33 proteins is an intricate and dynamic process. Two cryo-EM studies now provide insight into a complicated complex of at least 51 trans-factors that act on the preribosomal small subunit to sequentially fold it into a 3D molecular machine.

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Figure 1: Dissecting the small ribosomal subunit processome.

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Authors and Affiliations

  1. the Department of Medical Biochemistry and Biophysics, Karolinska Institutet, Stockholm, Sweden

    Joanna Rorbach

  2. the Department of Biochemistry and Biophysics, Science for Life Laboratory, Stockholm University, Solna, Sweden

    Shintaro Aibara & Alexey Amunts

Authors
  1. Joanna Rorbach
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  2. Shintaro Aibara
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  3. Alexey Amunts
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Correspondence to Alexey Amunts.

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The authors declare no competing financial interests.

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Rorbach, J., Aibara, S. & Amunts, A. Ribosome origami. Nat Struct Mol Biol 24, 879–881 (2017). https://doi.org/10.1038/nsmb.3497

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