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Chromatin-enriched lncRNAs: a novel class of enhancer RNAs

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Long noncoding (lnc)RNAs are postulated to control diverse biological processes by modulating transcription, yet for most lncRNAs evidence supporting this function has been lacking. A new report describes the role of a novel class of lncRNAs—chromatin-associated enhancer RNAs or cheRNAs—in the regulation of proximal gene expression.

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Figure 1: A schematic of cheRNA function.

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Authors and Affiliations

  1. the Department of Human Genetics, University of Michigan Medical School, Ann Arbor, Michigan, USA

    Srimonta Gayen & Sundeep Kalantry

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  1. Srimonta Gayen
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  2. Sundeep Kalantry
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Correspondence to Srimonta Gayen or Sundeep Kalantry.

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The authors declare no competing financial interests.

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Gayen, S., Kalantry, S. Chromatin-enriched lncRNAs: a novel class of enhancer RNAs. Nat Struct Mol Biol 24, 556–557 (2017). https://doi.org/10.1038/nsmb.3430

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