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Pinpointing a puzzling polymerase

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One of the surprising discoveries in the genomic age was the presence in plant genomes of two noncanonical DNA-dependent RNA polymerases involved in small RNA–mediated gene silencing. Two recent studies map the binding sites of RNA polymerase V, uncovering new mysteries concerning the targeting and function of this enigmatic enzyme.

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Figure 1: Pol V binding sites.

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Correspondence to Rebecca A Mosher.

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Mosher, R. Pinpointing a puzzling polymerase. Nat Struct Mol Biol 19, 865–866 (2012). https://doi.org/10.1038/nsmb.2374

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