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Crystal structure at 2.8 Å resolution of anabolic ornithine transcarbamylase from Escherichia coli

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The 2.8 Å resolution crystal structure of E. coli ornithine transcarbamylase is presented, the first to be reported for the trimeric, anabolic enzyme.

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References

  1. Villeret, V., Tricot, C., Stalon, V. & Dideberg, O. Proc. Natl. Acad. Sci. USA 92, 10762–10766 (1995).

    Article  CAS  Google Scholar 

  2. Ke, H.-M., Honzatko, R.B. & Lipscomb, W.N. Proc. Natl. Acad. Sci. USA 81, 4037–4040 (1984).

    Article  CAS  Google Scholar 

  3. Stevens, R.C., Reinisch, K.M. & Lipscomb, W.N. Proc. Natl.Acad.Sci. USA 88, 6087–6091 (1991).

    Article  CAS  Google Scholar 

  4. Krause, K.L., Volz, K.W. & Lipscomb, W.N. J. Mol. Biol. 193, 527–553 (1987).

    Article  CAS  Google Scholar 

  5. Marshall, M. & Cohen, P.P. J. Biol. Chem. 255, 7296–7300 (1980).

    PubMed  CAS  Google Scholar 

  6. McDowall, S., Heeswijk, R. & Hoogenraad, N. Prot. Engng. 4, 73–77 (1990).

    Article  CAS  Google Scholar 

  7. Goldsmith, J.O., Lee, S., Zambidis, I. & Kuo, L.C. J. Biol. Chem. 266, 18626–18634 (1991).

    PubMed  CAS  Google Scholar 

  8. Murata, L.B. & Schachman, H.K. Prot. Sci. 5: 709–718 (1996).

    Article  CAS  Google Scholar 

  9. Baburina, I. et al. Biochemistry 35, 10249–10255 (1996).

    Article  CAS  Google Scholar 

  10. Kuo, L.C., Herzberg, W. & Lipscomb, W.N. Biochemistry 24, 4754–4761 (1985).

    Article  CAS  Google Scholar 

  11. Lee, S., Miller, A.W., Shen, W.-H. & Kuo, L.C. J. Mol. Biol. 211, 255–269 (1990).

    Article  CAS  Google Scholar 

  12. Kuo, L.C., Caron, C., Lee, S. & Herzberg, W. J. Mol. Biol. 211, 271–280 (1990).

    Article  CAS  Google Scholar 

  13. Kuo, L.C. & Seaton, B.A. J. Biol. Chem. 264, 16246–16248 (1989).

    PubMed  CAS  Google Scholar 

  14. Otwinowski, Z. DENZO: An oscillation data processing program for protein crystallography (Yale University, New Haven, Connecticut; 1993).

    Google Scholar 

  15. Tong, L. & Rossman, M.G. Acta Crystallogr. A46, 783–792 (1990).

    Article  CAS  Google Scholar 

  16. Sheldrick, G.M., Dauter, Z., Wilson, K.S., Hope, H. & Sieker, L.C. Acta Cryst. D49, 18–23 (1993).

    CAS  Google Scholar 

  17. Navaza, J. Acta Crystallogr. A50, 157–163 (1994).

    Article  CAS  Google Scholar 

  18. Kabsch, W., Mannherz, H.G., Suck, D., Pai, E.F. & Holmes, K. Nature 347 37–44.

  19. Jones, T.A. in Molecular replacement, proceedings of the CCP4 study weekend (eds Dodson, S., Gover, S., & Wolf, W.) 91–105 (Daresbury Laboratory, UK; 1992).

    Google Scholar 

  20. Brünger, A. X-PLOR Version 3.1 Manual. (Yale University, New Haven, Connecticut; 1993).

    Google Scholar 

  21. Jones, T.A. & Kjeldgaard, M. O — The Manual. (Uppsala, Sweden; 1992).

    Google Scholar 

  22. Brünger, A. Nature 335, 472–475 (1992).

    Article  Google Scholar 

  23. CCP4:Asuite of programs for protein crystallography. (SERC collaborative computing project No. 4, Daresbury Laboratory, Warrington UK; 1979).

  24. Laskowski, R.A., MacArthur, M.W., Moss, D.S. & Thornton, J.M. J. Appl. Crystallogr. 26, 282–291 (1993).

    Article  Google Scholar 

  25. Bernstein, F.C. et al. J. Mol. Biol. 112, 535–542 (1977).

    Article  CAS  Google Scholar 

  26. Kraulis, P.J. J. appl. Crystallogr. 24, 946–950 (1991).

    Article  Google Scholar 

  27. Yamamoto, A., Tomoo, K., Doi, M., Ohishi, H., Inoue, M., Ishida, T. et al. Biochemistry 31, 11305–11309. (1992).

    Article  CAS  Google Scholar 

  28. Pedersen, L.C., et al. Prot. Sci. 3, 1131–1135 (1994).

    Article  CAS  Google Scholar 

  29. Ollis, D.L. & Pathak, D. J. Mol. Biol. 214, 497–525 (1990).

    Article  Google Scholar 

  30. Dixon, M.M. & Matthews, B.W. Biochemistry 28, 7033–7038 (1989).

    Article  CAS  Google Scholar 

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Jin, L., Seaton, B. & Head, J. Crystal structure at 2.8 Å resolution of anabolic ornithine transcarbamylase from Escherichia coli. Nat Struct Mol Biol 4, 622–625 (1997). https://doi.org/10.1038/nsb0897-622

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