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Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone

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The first structure of a sea anemone potassium channel toxin reveals how a novel structural scaffold can be used to present key functional groups for channel blockade.

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Authors and Affiliations

  1. NMR Laboratory, Biomolecular Research Institute, 381 Royal Parade, Parkville, 3052, Australia

    Jane E. Tudor, Paul K. Pallaghy & Raymond S. Norton

  2. Bachem Bioscience Inc., 3700 Horizon Drive, King of Prussia, Pennsylvania, 19406, USA

    Michael W. Pennington

Authors
  1. Jane E. Tudor
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  2. Paul K. Pallaghy
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  3. Michael W. Pennington
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  4. Raymond S. Norton
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Tudor, J., Pallaghy, P., Pennington, M. et al. Solution structure of ShK toxin, a novel potassium channel inhibitor from a sea anemone. Nat Struct Mol Biol 3, 317–320 (1996). https://doi.org/10.1038/nsb0496-317

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  • DOI: https://doi.org/10.1038/nsb0496-317

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