A new structure brings into sharp focus the structural basis for G–C base pair recognition by small ligands in the minor groove of DNA. At the same time the ability to distinguish specific sequences moves another major step forward through introduction of a new ligand modification.
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References
Kielkopf, C.L. et al. Nature Struct. Biol. 5, 104–109 (1998).
White, S. et al. Nature 391, 468–471 (1998).
Kopka, M.L. et al. J. Mol. Biol. 183, 553–563 (1985).
Pelton, J.G. & Wemmer, D.E. Proc. Natl. Acad. Sci. USA 86, 5723–5727 (1989).
Kopka, M.L. et al. Proc. Natl. Acad. Sci. USA 82, 1376–1380 (1985).
Lown, J.W. et al. Biochemistry 25, 7408–7416 (1986).
Lown, J.W. J. Mol. Recog. 7, 79–88 (1994).
Wade, W.S., Mrksich, M. & Dervan, P.B. J. Am. Chem. Soc. 114, 8783–8794 (1992).
Dwyer, T.J. et al. J. Am. Chem. Soc. 114, 5911–5919 (1992).
Geierstanger, B.H. et al. J. Am. Chem. Soc. 115, 4474–4482 (1993).
Geierstanger, B.H. et al. Science 266, 646–650 (1994).
Heinemann, U. J. Mol. Biol. 223, 369–381 (1989).
Mrksich, M. & Dervan, P.B. J. Am. Chem. Soc. 115, 9892–9899 (1993).
Mrksich, M., Parks, M.E. & Dervan, P.B. J. Am. Chem. Soc. 116, 7983–7988 (1994).
de Clairac, R.P.L. et al. J. Am. Chem. Soc. 119, 7909–7916 (1997).
Turner, J.M., Baird, E.E. & Dervan, P.B. J. Am. Chem. Soc. 119, 7636–7644 (1997).
Kelly, J.J., Baird, E.E. & Dervan, P.B. Proc. Natl. Acad. Sci. USA 93, 6981–6985 (1996).
Trauger, J.W., et al. J. Am. Chem. Soc. 118, 6160–6166 (1996).
Geierstanger et al. Nature Struct. Biol. 3, 321–324 (1996).
Gottesfeld, J.M. et al. Nature 387, 202–205 (1997).
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Wemmer, D. Reading DNA. Nat Struct Mol Biol 5, 169–171 (1998). https://doi.org/10.1038/nsb0398-169
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DOI: https://doi.org/10.1038/nsb0398-169
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