The difficult task of providing an atomic-level picture of integrin adhesion is beginning to bear fruit with the determination of the crystal structure of an α-chain sub-domain that has primary ligand-binding epitopes.
This is a preview of subscription content, log in via an institution to check access.
References
Lee, J.-O., Rieu, P., Arnaout, M.A. & Liddington, R. Cell 80, in the press.
Graves, B.J. et al. Nature 367, 532–538 (1994).
Arnaout, M.A., Gupta, S.K., Pierce, M.W. & Tenen, D.G. J. cell Biol. 106, 2153–2158 (1988).
Michishita, M., Videm, V. & Arnaout, M.A. Cell 72, 857–867 (1993).
Ueda, T., Rieu, P., Brayer, J. & Arnaout, M.A. Proc. natn. Acad. Sci. U.S.A. 91, 10680–10684 (1994).
Rieu, P., Ueda, T., Haruta, I., Sharma, C.P. & Arnaout, M.A. J. cell Biol. 127, 2081–2091 (1994).
Kamata, T., Puzon, W. & Takada, Y. J. biol. Chem. 269, 9659–9663 (1994).
Randi, A.M. & Hogg, N. J. biol. Chem. 269, 12395–12398 (1994).
Zhou, L., Lee, D.H.S., Plescia, J., Lau, C.Y. & Altieri, D.C. J. biol. Chem. 269, 17075–17079 (1994).
Kern, A., Briesewitz, R., Bank, I. & Marcantonio, E.E. J. biol. Chem. 269, 22811–22816 (1994).
Diamond, M.S., Garcia-Aguilar, J., Bickford, J.K., Corbi, A.L. & Springer, T.A. J. cell Biol. 120, 1031–1043 (1993).
Takada, Y. & Hemler, M.E. J. cell Biol. 109, 397–407 (1989).
Branden, C. & Tooze, J. Introduction to Protein Structure, 43–57 (Garland Publishing, 1991).
Gailit, J. & Ruoslahti, E. J. biol. Chem. 263, 12927–12932 (1988).
Hynes, R.O. Cell 69, 11–25 (1992).
Taniguchi-Sidle, A. & Isenman, D.E. J. Immunol. 153, 5285–5302 (1994).
Staunton, D.E., Dustin, M.L., Erickson, H.P. & Springer, T.A. Cell 61, 243–254 (1990).
Altieri, D.C. J. Immunol. 147, 1891–1898 (1991).
Dransfield, I., Cabañas, C., Craig, A. & Hogg, N., J. cell Biol. 116, 219–226 (1992).
Bodian, D.L., Bottomley, M., Harlos, K., Jones, E.Y. & Stuart, D.I. Nature 373, in the press (1995).
Nicholls, A. GRASP: Graphical Representation and Analysis of Surface Properties (Columbia University, 1992).
Tamkun, J.W. et al. Cell 46, 271–282 (1986).
Hynes, R.O. Cell 48, 549–554 (1987).
Larson, R.S., Corbi, A.L., Berman, L. & Springer, T. J. cell Biol. 108, 703–712 (1989).
Colombatti, A. & Bonaldo, P. Blood 77, 2305–2315 (1991).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Graves, B. Integrin binding revealed. Nat Struct Mol Biol 2, 181–183 (1995). https://doi.org/10.1038/nsb0395-181
Issue Date:
DOI: https://doi.org/10.1038/nsb0395-181
- Springer Nature America, Inc.