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Kidney cancer in 2017

Challenging and refining treatment paradigms

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Treatment paradigms for advanced renal cell carcinoma (RCC) continue to be challenged and refined. Recent studies in metastatic RCC have demonstrated the efficacy of first-line cabozantinib and the safety and efficacy of dual checkpoint blockade; in the adjuvant setting, pazopanib failed to improve progression-free survival in high-risk localized RCC compared with placebo.

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Authors and Affiliations

  1. Mark W. Ball and Ramaprasad Srinivasan are at the Urologic Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 10 Center Drive, CRC2-5950, Bethesda, Maryland 20892, USA.,

    Mark W. Ball & Ramaprasad Srinivasan

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  1. Mark W. Ball
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  2. Ramaprasad Srinivasan
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Correspondence to Ramaprasad Srinivasan.

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The authors declare no competing financial interests.

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Ball, M., Srinivasan, R. Challenging and refining treatment paradigms. Nat Rev Urol 15, 77–78 (2018). https://doi.org/10.1038/nrurol.2017.220

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