Skip to main content

Advertisement

Log in

UTUC in 2017

Emerging evidence on treating upper tract urothelial cancer

  • Year in Review
  • Published:

From Nature Reviews Urology

View current issue Sign up to alerts

Major advances in the management of all stages of upper tract urothelial carcinoma have been made in 2017. Radical nephroureterectomy can be valuable in patients with metastatic disease and adjuvant platinum-based chemotherapy can improve outcomes in those with advanced disease. Kidney-sparing surgery with early follow-up ureterorenoscopy has shown benefit in patients with low-grade tumours. Avoiding unnecessary ureterorenoscopy might decrease intravesical tumour recurrence.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Rouprêt, M. et al. European Association of Urology Guidelines on Upper Urinary Tract Urothelial Carcinoma: 2017 Update. Eur. Urol. http://dx.doi.org/10.1016/j.eururo.2017.07.036 (2017).

  2. Seisen, T. et al. Efficacy of Systemic Chemotherapy Plus Radical Nephroureterectomy for Metastatic Upper Tract Urothelial Carcinoma. Eur. Urol. 71, 714–718 (2017).

    Article  Google Scholar 

  3. Seisen, T. et al. Effectiveness of adjuvant chemotherapy after radical nephroureterectomy for locally advanced and/or positive regional lymph node upper tract urothelial carcinoma. J. Clin. Oncol. 35, 852–860 (2017).

    Article  Google Scholar 

  4. Seisen, T. et al. Oncologic outcomes of kidney-sparing surgery versus radical nephroureterectomy for upper tract urothelial carcinoma: a systematic review by the EAU non-muscle invasive bladder cancer guidelines panel. Eur. Urol. 70, 1052–1068 (2016).

    Article  Google Scholar 

  5. Villa, L. et al. Early repeated ureteroscopy within 6–8 weeks after a primary endoscopic treatment in patients with upper tract urothelial cell carcinoma: preliminary findings. World J. Urol. 34, 1201–1206 (2016).

    Article  Google Scholar 

  6. Marchioni, M. et al. Impact of diagnostic ureteroscopy on intravesical recurrence in patients undergoing radical nephroureterectomy for upper tract urothelial cancer: a systematic review and meta-analysis. BJU Int. 120, 313–319 (2017).

    Article  Google Scholar 

  7. Breda, A. et al. Correlation between confocal laser endomicroscopy (Cellvizio®) and histological grading of upper tract urothelial carcinoma: a step forward for a better selection of patients suitable for conservative management. Eur. Urol. Focus http://dx.doi.org/10.1016/j.euf.2017.05.008 (2017).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Morgan Rouprêt.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Grande, P., Rouprêt, M. Emerging evidence on treating upper tract urothelial cancer. Nat Rev Urol 15, 73–74 (2018). https://doi.org/10.1038/nrurol.2017.203

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrurol.2017.203

  • Springer Nature Limited

Navigation