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Predicting stone episodes using cystine capacity

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Cystine capacity is an assay for assessing urinary cystine saturation and risk of a stone episode in patients with cystinuria. Lowering the threshold for this test improves its sensitivity, potentially enabling relaxation of follow-up regimens for patients at lowest risk of stone episodes and dose modification of medications for those at highest risk.

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Figure 1: Distribution of cystine capacity measurements in a recent study of 48 patients with cystinuria.

References

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Authors and Affiliations

  1. Matthew Bultitude and Kay Thomas are at the Stone Unit, Guy's and St Thomas' NHS Foundation Trust, 1st Floor Southwark Wing, Guy's Hospital, Great Maze Pond, London SE1 9RT, UK.,

    Matthew Bultitude & Kay Thomas

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  1. Matthew Bultitude
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  2. Kay Thomas
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Correspondence to Matthew Bultitude or Kay Thomas.

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The authors declare no competing financial interests.

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Bultitude, M., Thomas, K. Predicting stone episodes using cystine capacity. Nat Rev Urol 15, 8–9 (2018). https://doi.org/10.1038/nrurol.2017.189

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  • DOI: https://doi.org/10.1038/nrurol.2017.189

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