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Kidney cancer

Treatment of clinically localized renal tumors in the elderly

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There are several options for treating clinically localized renal tumors in the elderly, ranging from active surveillance to radical nephrectomy. Reduced renal function is associated with increased cardiovascular mortality, so maintaining renal function is of the utmost importance. Personalized therapy should be based on tumor location, comorbidities and general health status rather than tumor size and patient age.

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References

  1. Campbell, S. C. et al. Guideline for management of the clinical T1 renal mass. J. Urol. 182, 1271–1279 (2009).

    Article  PubMed  Google Scholar 

  2. Lai, F. C., Kau, E. L., Ng, C. S. & Fuchs, G. J. Laparoscopic nephrectomy outcomes of elderly patients in the 21st century. J. Endourol. 21, 1309–1313 (2007).

    Article  PubMed  Google Scholar 

  3. Iseki, K., Ikemiya, Y. & Fukiyama, K. Risk factors of end-stage renal disease and serum creatinine in a community-based mass screening. Kidney Int. 51, 850–854 (1997).

    Article  CAS  Google Scholar 

  4. Kates, M., Badalato, G., Pitman, M. & McKiernan, J. Persistent overuse of radical nephrectomy in the elderly. Urology 78, 555–559 (2011).

    Article  PubMed  Google Scholar 

  5. Lowrance, W. T. et al. Complications after radical and partial nephrectomy as a function of age. J. Urol. 183, 1725–1730 (2010).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Roos, F. C. et al. Perioperative morbidity and renal function in young and elderly patients undergoing elective nephron-sparing surgery or radical nephrectomy for renal tumors larger than 4 cm. BJU Int. 107, 554–561 (2011).

    Article  PubMed  Google Scholar 

  7. Breau, R. H. et al. Outcome of stage T2 or greater renal cell cancer treated with partial nephrectomy. J. Urol. 183, 903–908 (2010).

    Article  PubMed  Google Scholar 

  8. Roos, F. C., Hampel, C. & Thuroff, J. W. Renal cancer surgery in the elderly. Curr. Opin. Urol. 19, 459–464 (2009).

    Article  PubMed  Google Scholar 

  9. Huang, W. C. et al. Chronic kidney disease after nephrectomy in patients with renal cortical tumors: a retrospective cohort study. Lancet Oncol. 7, 735–740 (2006).

    Article  PubMed  PubMed Central  Google Scholar 

  10. Kaouk, J. H., Goel, R. K., Haber, G. P., Crouzet, S. & Stein, R. J. Robotic single-port transumbilical surgery in humans: initial report. BJU Int. 103, 366–369 (2009).

    Article  PubMed  Google Scholar 

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Correspondence to Joachim W. Thüroff.

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Roos, F., Thüroff, J. Treatment of clinically localized renal tumors in the elderly. Nat Rev Urol 8, 595–596 (2011). https://doi.org/10.1038/nrurol.2011.151

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  • DOI: https://doi.org/10.1038/nrurol.2011.151

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