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Regenerative medicine

Self-directed articular resurfacing: a new paradigm?

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From Nature Reviews Rheumatology

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Tissue engineering to repair diseased or injured cartilage could be revolutionized by the development of a novel cell-homing strategy that overcomes several barriers inherent in the use of existing techniques.

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Figure 1: A cell-homing approach to joint-surface regeneration.

References

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Authors and Affiliations

  1. The Feinstein Institute for Medical Research, 350 Community Drive, Manhasset, 11030, NY, USA

    Daniel A. Grande

  2. Department of Orthopedics, Long Island Jewish Medical Center, 600 Northern Boulevard, Great Neck, 11021, NY, USA

    Nicholas A. Sgaglione

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  1. Daniel A. Grande
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  2. Nicholas A. Sgaglione
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Correspondence to Daniel A. Grande.

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Competing interests

D. A. Grande has acted as a consultant for Arthrocare and TiGenix, and has received grant/research support from and is a stockholder/director of TiGenix. N. Sgaglione has acted as a consultant for Biomet Sports Medicine, ConMed Linvatec and Smith and Nephew Endoscopy, and is a patent holder/applicant for a Biomet Sports Medicine product.

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Grande, D., Sgaglione, N. Self-directed articular resurfacing: a new paradigm?. Nat Rev Rheumatol 6, 677–678 (2010). https://doi.org/10.1038/nrrheum.2010.192

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