The past year saw advances in endovascular treatment for acute stroke, speech therapy for aphasia after stroke, and cardiac disease management to prevent stroke. These treatments were characterized by more intensive or more extensive effects than standard care, necessitating thoughtful translation of the clinical trial findings into routine clinical practice.
References
van den Berg, L. A. et al. Two-year outcome after endovascular treatment for acute ischemic stroke. N. Engl. J. Med. 376, 1341–1349 (2017).
Nogueira, R. G. et al. Thrombectomy 6 to 24 hours after stroke with a mismatch between deficit and infarct. N. Engl. J. Med. https://doi.org/10.1056/NEJMoa1706442 (2017).
Mas, J. L. et al. Patent foramen ovale closure or anticoagulation versus antiplatelets after stroke. N. Engl. J. Med. 377, 1011–1021 (2017).
Søndergaard, L. et al. Patent foramen ovale closure or antiplatelet therapy for cryptogenic stroke. N. Engl. J. Med. 377, 1033–1042 (2017).
Saver, J. L. et al. Long-term outcomes of patent foramen ovale closure or medical therapy after stroke. N. Engl. J. Med. 377, 1022–1032 (2017).
De Caterina, R. et al. Valvular heart disease patients on edoxaban or warfarin in the ENGAGE AF–TMI 48 trial. J. Am. Coll. Cardiol. 69, 1372–1382 (2017).
Pan, K. L. et al. Effects of non-vitamin K antagonist oral anticoagulants versus warfarin in patients with atrial fibrillation and valvular heart disease: a systematic review and meta-analysis. J. Am. Heart Assoc. 6, e005835 (2017).
Breitenstein, C. et al. Intensive speech and language therapy in patients with chronic aphasia after stroke: a randomised, open-label, blinded-endpoint, controlled trial in a health-care setting. Lancet 389, 1528–1538 (2017).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Lee, M., Ovbiagele, B. Intensive and extensive — advances in stroke management. Nat Rev Neurol 14, 68–70 (2018). https://doi.org/10.1038/nrneurol.2017.187
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrneurol.2017.187
- Springer Nature Limited