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Parkinson disease

What goes around comes around: cognitive impairment as prodromal parkinsonism?

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Patients with prodromal Parkinson disease (PD) are most likely to respond to disease-modifying strategies. To date, cognitive impairment has been viewed as a complication of late-stage disease, but a longitudinal analysis of data from the Rotterdam cohort raises the possibility that such impairments are also associated with prodromal PD.

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Acknowledgements

Y.C. and M.J.M. gratefully acknowledge financial support from the CERCA Programme of the Generalitat de Catalunya (Barcelona, Catalonia, Spain).

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Authors and Affiliations

  1. Yaroslau Compta is at the Parkinson's Disease and Movement Disorders Unit of the Neurology Service of Hospital Clinic/IDIBAPS/CIBERNED; and at the Department of Biomedicine of the University of Barcelona, 170 Villarroel, 08036, Barcelona, Catalonia, Spain.,

    Yaroslau Compta

  2. and at the Department of Biomedicine of the University of Barcelona, 170 Villarroel, 08036, Barcelona, Catalonia, Spain.,

    Yaroslau Compta

  3. Maria J. Martí is at the Parkinson's Disease and Movement Disorders Unit of the Neurology Service of Hospital Clinic/IDIBAPS/CIBERNED; and at the Department of Medicine of the University of Barcelona, 170 Villarroel, 08036, Barcelona, Catalonia, Spain.,

    Maria J. Martí

  4. and at the Department of Medicine of the University of Barcelona, 170 Villarroel, 08036, Barcelona, Catalonia, Spain.,

    Maria J. Martí

Authors
  1. Yaroslau Compta
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  2. Maria J. Martí
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Correspondence to Maria J. Martí.

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The authors declare no competing financial interests.

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Compta, Y., Martí, M. What goes around comes around: cognitive impairment as prodromal parkinsonism?. Nat Rev Neurol 13, 709–710 (2017). https://doi.org/10.1038/nrneurol.2017.159

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