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Parkinson disease

Insect screens for PD therapies — keep the flies in

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Two new studies report on the potential of a number of antioxidants and a cholesterol-lowering drug to prevent neurodegeneration in a Drosophila genetic model of parkinsonism. This research shines a spotlight on the power of invertebrate models as an in vivo screening tool.

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Authors and Affiliations

  1. Department of Neurology, Ian Martin and Vinita G. Chittoor are at the Jungers Center for Neurosciences Research, Parkinson Center of Oregon, Oregon Health & Science University, 3181 SW Sam Jackson Park Road, Portland, Oregon 97239, USA.,

    Ian Martin & Vinita G. Chittoor

Authors
  1. Ian Martin
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  2. Vinita G. Chittoor
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Correspondence to Ian Martin.

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The authors declare no competing financial interests.

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Martin, I., Chittoor, V. Insect screens for PD therapies — keep the flies in. Nat Rev Neurol 12, 318–319 (2016). https://doi.org/10.1038/nrneurol.2016.56

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