The recent DOMINO-AD trial suggests that continued treatment with donepezil delays nursing home placement for patients with severe Alzheimer disease, but more work is needed to support strong conclusions about whether the benefits outweigh the costs.
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Jelic, V., Winblad, B. Donepezil and nursing home placement — benefits and costs. Nat Rev Neurol 12, 11–13 (2016). https://doi.org/10.1038/nrneurol.2015.237
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DOI: https://doi.org/10.1038/nrneurol.2015.237
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