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Parkinson disease

Unravelling the nonmotor mysteries of Parkinson disease

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Parkinson disease (PD) is now regarded as a mixed motor, nonmotor and multiorgan disorder rather than a pure movement disorder. Nonmotor symptoms (NMS) have underpinned this conceptual change, and new criteria for clinical and prodromal diagnosis of PD, incorporating a range of NMS, have recently been published.

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Figure 1: Proposed flowchart for research and diagnosis in prodromal Parkinson disease (PD).

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Authors and Affiliations

  1. Maurice Wohl Clinical Neuroscience Institute, King's College London, 5 Cutcombe Road, London, SE5 9RT, UK

    K. Ray Chaudhuri & Anna Sauerbier

Authors
  1. K. Ray Chaudhuri
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  2. Anna Sauerbier
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Corresponding author

Correspondence to K. Ray Chaudhuri.

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The authors declare no competing financial interests.

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Chaudhuri, K., Sauerbier, A. Unravelling the nonmotor mysteries of Parkinson disease. Nat Rev Neurol 12, 10–11 (2016). https://doi.org/10.1038/nrneurol.2015.236

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