Medulloblastomas can be categorized into four molecular subgroups. A new report shows, for the first time, that these tumours remain in the same subgroup at relapse, and the molecular subgroup influences the pattern of relapse. These findings indicate that this developmentally defined classification is robust, although its relationship to prognosis remains uncertain.
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Grill, J., Dufour, C. Stability of medulloblastoma subgroups at tumour recurrence. Nat Rev Neurol 10, 5–6 (2014). https://doi.org/10.1038/nrneurol.2013.256
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DOI: https://doi.org/10.1038/nrneurol.2013.256
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