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Neuromuscular disease

Acute treatment for myasthenia gravis

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Acute exacerbations of myasthenia gravis (MG) need effective and urgent treatment because of life-threatening hypoventilation. Plasma exchange and intravenous immunoglobulin (IVIg) are both effective for acute MG. A new study suggests that these treatments produce similar patient outcomes and complications, with IVIg perhaps being superior from an economic perspective.

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References

  1. Skeie, G. O. et al. Guidelines for treatment of autoimmune neuromuscular transmission disorders. Eur. J. Neurol. 17, 893–902 (2010).

    Article  CAS  Google Scholar 

  2. Jani-Acsadi, A. & Lisak, R. P. Myasthenia gravis. Curr. Treat. Options Neurol. 12, 231–243 (2010).

    Article  Google Scholar 

  3. Mandawat, A., Kaminski, H. J., Cutter, G., Katirji, B. & Alsheklee, A. Comparative analysis of therapeutic options used for myasthenia gravis. Ann. Neurol. 68, 797–805 (2010).

    Article  Google Scholar 

  4. Owe, J. F., Daltveit, A. K. & Gilhus, N. E. Causes of death among patients with myasthenia gravis in Norway between 1951 and 2001. J. Neurol. Neurosurg. Psychiat. 77, 203–207 (2006).

    Article  CAS  Google Scholar 

  5. Gilhus, N. E. Autoimmune myasthenia gravis. Expert Rev. Neurother. 9, 351–358 (2009).

    Article  CAS  Google Scholar 

  6. Cabrera Serrano, M. & Rabinstein, A. A. Causes and outcomes of acute neuromuscular respiratory failure. Arch. Neurol. 67, 1089–1094 (2010).

    Article  Google Scholar 

  7. Gajdos, P., Chevret, S. & Toyka, K. V. Intravenous immunoglobulin for myasthenia gravis. Cochrane Database of Systematic Reviews Issue 1, Art. No.: CD002277. doi: 10.1002/14651858.CD002277.pub3 (2008).

  8. Simoens, S. The use of intravenous immunoglobulins in Belgium. Int. Arch. Allergy Immunol. 154, 173–176 (2011).

    Article  CAS  Google Scholar 

  9. Elovaara, I. et al. EFNS guidelines for the use of intravenous immunoglobulin in treatment of neurological diseases. Eur. J. Neurol. 15, 893–908 (2008).

    Article  CAS  Google Scholar 

  10. Alshekhlee, A., Miles, J. D., Katirji, B., Preston, D. C. & Kaminski, H. J. Incidence and mortality rates of myasthenia gravis and myasthenic crisis in US hospitals. Neurology 72, 1548–1554 (2009).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Clinical Medicine, University of Bergen, PO Box 7800, Bergen, 5020, Norway

    Nils Erik Gilhus

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  1. Nils Erik Gilhus
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Gilhus, N. Acute treatment for myasthenia gravis. Nat Rev Neurol 7, 132–134 (2011). https://doi.org/10.1038/nrneurol.2011.14

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