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Dementia

Poststroke dementia—what's in a name?

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Poststroke dementia is a clinically heterogeneous syndrome with various underlying mechanisms. A better understanding of the pathophysiology of poststroke dementia together with an improved ability to differentiate between various dementia syndromes will be useful for optimizing therapeutic interventions, and for informing patients and carers about treatment options and prognosis.

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References

  1. WHO. The World Health Report 2002: reducing risks, promoting healthy life. The World Heath Report [online], (2009).

  2. Leys, D., Hénon, H., Mackowiak-Cordoliani, M. & Pasquier, F. Poststroke dementia. Lancet Neurol. 4, 752–759 (2005).

    Article  Google Scholar 

  3. Pendlebury, S. T. & Rothwell, P. M. Prevalence, incidence, and factors associated with pre-stroke and post-stroke dementia: a systematic review and meta-analysis. Lancet Neurol. 8, 1006–1018 (2009).

    Article  Google Scholar 

  4. Blennow, K. & Hampel, H. CSF markers for incipient Alzheimer's disease. Lancet Neurol. 2, 605–613 (2003).

    Article  CAS  Google Scholar 

  5. Klunk, W. E. et al. Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B. Ann. Neurol. 55, 306–319 (2004).

    Article  CAS  Google Scholar 

  6. de Jong, D., Jansen, R. W., Kremer, B. P. & Verbeek, M. M. Cerebrospinal fluid amyloid β42/phophorylated tau ratio discrimates between Alzheimer's disease and vascular dementia. J. Gerontol. A Biol. Sci. Med. Sci. 61, 755–758 (2006).

    Article  Google Scholar 

  7. Román, G. C. et al. Vascular dementia: diagnostic criteria for research studies. Report of the NINDS–AIREN International Workshop. Neurology 43, 250–260 (1993).

    Article  Google Scholar 

  8. Snaphaan, L., Rijpkema, M., van Uden, I., Fernández, G. & de Leeuw, F. E. Reduced medial temporal lobe functionality in stroke patients: a functional magnetic resonance imaging study. Brain 132, 1882–1888 (2009).

    Article  Google Scholar 

  9. Fratiglioni, L., Paillard-Borg, S. & Winblad, B. An active and socially integrated lifestyle in late life might protect against dementia. Lancet Neurol. 3, 343–353 (2004).

    Article  Google Scholar 

  10. van Praag, H. Exercise and the brain: something to chew on. Trends Neurosci. 32, 283–290 (2009).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Neurology, Donders Center for Neuroscience, Medical Center, Radboud University Nijmegen, P. O. Box 9101, 6500, HB Nijmegen, The Netherlands

    Anil M. Tuladhar & Frank-Erik de Leeuw

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  1. Anil M. Tuladhar
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  2. Frank-Erik de Leeuw
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Correspondence to Frank-Erik de Leeuw.

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The authors declare no competing financial interests.

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Tuladhar, A., de Leeuw, FE. Poststroke dementia—what's in a name?. Nat Rev Neurol 6, 63–64 (2010). https://doi.org/10.1038/nrneurol.2009.229

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