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Genetics of kidney diseases in 2017

Unveiling the genetic architecture of kidney disease

  • Year in Review
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From Nature Reviews Nephrology

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Technical advances in genome sequencing and association studies have yielded critical insights into the genetic architecture of kidney diseases. Here, I summarize four key studies from 2017 that deciphered the genetic basis of known and novel diseases and provided insights into the mechanisms of glomerular, developmental defects and manifestations of kidney disorders.

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Figure 1: Novel pathways involved in congenital kidney disorders.

References

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Authors and Affiliations

  1. Institute of Physiology, University of Zurich, Winterthurerstrasse 190, Zürich, CH-8057, Switzerland

    Olivier Devuyst

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  1. Olivier Devuyst
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Correspondence to Olivier Devuyst.

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The author declares no competing financial interests.

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Devuyst, O. Unveiling the genetic architecture of kidney disease. Nat Rev Nephrol 14, 80–82 (2018). https://doi.org/10.1038/nrneph.2017.177

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