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Decade in review—polycystic kidney disease

Slowing progression of autosomal dominant polycystic kidney disease

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Autosomal dominant polycystic kidney disease is a challenging disorder to diagnose and treat effectively. Promising research over the past decade has, however, provided novel interventions, modifications to clinical practice and new areas to investigate with the aim of identifying approaches to slow disease progression.

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Figure 1: Pathogenic role of the renin–angiotensin–aldosterone system in ADPKD.

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Authors and Affiliations

  1. Division of Renal Diseases and Hypertension, University of Colorado Denver, 12700 East 19th Avenue, Campus Box C281, Aurora, 80045, CO, USA

    Robert W. Schrier

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  1. Robert W. Schrier
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Correspondence to Robert W. Schrier.

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The author declares no competing financial interests.

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Schrier, R. Slowing progression of autosomal dominant polycystic kidney disease. Nat Rev Nephrol 11, 638–639 (2015). https://doi.org/10.1038/nrneph.2015.164

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