Skip to main content
Log in

Dialysis

A step towards making online haemodiafiltration a gold standard

  • News & Views
  • Published:

From Nature Reviews Nephrology

View current issue Sign up to alerts

Online haemodiafiltration is the most advanced dialysis treatment currently available, but widespread implementation of this technique has been delayed pending conclusive evidence of its benefits from randomized studies. The results of the randomized, controlled ESHOL study are now available. Will they change practice?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Locatelli, F. & Canaud, B. Dialysis adequacy today: a European perspective. Nephrol. Dial. Transplant. 27, 3043–3048 (2012).

    Article  CAS  Google Scholar 

  2. Locatelli, F. et al. Effect of membrane permeability on survival of hemodialysis patients. J. Am. Soc. Nephrol. 20, 645–654 (2009).

    Article  Google Scholar 

  3. Locatelli, F. et al. Hemofiltration and hemodiafiltration reduce intradialytic hypotension in ESRD. J. Am. Soc. Nephrol. 21, 1798–1807 (2010).

    Article  CAS  Google Scholar 

  4. Canaud, B. et al. Mortality risk for patients receiving hemodiafiltration versus hemodialysis: European results from the DOPPS. Kidney Int. 69, 2087–2093 (2006).

    Article  CAS  Google Scholar 

  5. Locatelli, F. et al. Effects of different membranes and dialysis technologies on patient treatment tolerance and nutritional parameters. The Italian Cooperative Dialysis Study Group. Kidney Int. 50, 1293–1302 (1996).

    Article  CAS  Google Scholar 

  6. Wizemann, V., Külz, M., Techert, F. & Nederlof, B. Efficacy of haemodiafiltration. Nephrol. Dial. Transplant. 16 (Suppl. 4), 27–30 (2001).

    Article  CAS  Google Scholar 

  7. Grooteman, M. P. et al. Effect of online hemodiafiltration on all-cause mortality and cardiovascular outcomes. J. Am. Soc. Nephrol. 23, 1087–1096 (2012).

    Article  CAS  Google Scholar 

  8. Ok, E. et al. Mortality and cardiovascular events in online haemodiafiltration (OL-HDF) compared with high-flux dialysis: results from the Turkish OL-HDF Study. Nephrol. Dial. Transplant. http://dx.doi.org/10.1093/ndt/gfs407.

  9. Maduell, F. et al. High-efficiency postdilution online hemodiafiltration reduces all-cause mortality in hemodialysis patients. J. Am. Soc. Nephrol. 24, 487–498 (2013).

    Article  Google Scholar 

  10. Tattersall, J. E., Ward, R. A. & EUDIAL group. Online haemodiafiltration: definition, dose quantification and safety revisited. Nephrol. Dial. Transplant. 28, 542–550 (2013).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Francesco Locatelli.

Ethics declarations

Competing interests

F. Locatelli has been a speaker at meetings supported by Bellco, Braun, Fresenius and Gambro–Hospal. W. H. Hörl has been a speaker at meetings supported by Braun and Fresenius.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Locatelli, F., Hörl, W. A step towards making online haemodiafiltration a gold standard. Nat Rev Nephrol 9, 316–318 (2013). https://doi.org/10.1038/nrneph.2013.75

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrneph.2013.75

  • Springer Nature Limited

This article is cited by

Navigation