Skip to main content

Advertisement

Log in

Dialysis

Glycated albumin or HbA1c in dialysis patients with diabetes?

  • News & Views
  • Published:

From Nature Reviews Nephrology

View current issue Sign up to alerts

Levels of glycated albumin seem to predict mortality and hospitalization more accurately than does levels of glycated hemoglobin in patients with diabetes mellitus who are on dialysis. Should we be measuring glycated albumin instead of glycated hemoglobin in this group of patients?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Freedman, B. I. et al. Glycated albumin and risk of death and hospitalizations in diabetic dialysis patients. Clin. J. Am. Soc. Nephrol. 6, 1635–1643 (2011).

    Article  CAS  Google Scholar 

  2. Inaba, M. et al. Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: effect of anemia and erythropoietin injection. J. Am. Soc. Nephrol. 18, 896–903 (2007).

    Article  CAS  Google Scholar 

  3. Shurraw, S., Majumdar, S. R., Thadhani, R., Wiebe, N. & Tonelli, M. Glycemic control and the risk of death in 1484 patients receiving maintenance hemodialysis. Am. J. Kidney Dis. 55, 875–884 (2010).

    Article  Google Scholar 

  4. Vlassara, H. & Palace, M. R. Diabetes and advanced glycation endproducts. J. Intern. Med. 251, 87–101 (2002).

    Article  CAS  Google Scholar 

  5. Kalantar-Zadeh, K. et al. A1C and survival in maintenance hemodialysis patients. Diabetes Care 30, 1049–1055 (2007).

    Article  Google Scholar 

  6. Uzu, T. et al. Target for glycemic control in type 2 diabetic patients on hemodialysis: effects of anemia and erythropoietin injection on hemoglobin A1c. Ther. Apher. Dial. 13, 89–94 (2009).

    Article  CAS  Google Scholar 

  7. Nagayama, H. et al. Glycated albumin as an improved indicator of glycemic control in hemodialysis patients with type 2 diabetes based on fasting plasma glucose and oral glucose tolerance test. Biomed. Pharmacother. 63, 236–240 (2009).

    Article  CAS  Google Scholar 

  8. Okada, T. et al. Association between markers of glycemic control, cardiovascular complications and survival in type 2 diabetic patients with end-stage renal disease. Intern. Med. 46, 807–814 (2007).

    Article  Google Scholar 

  9. Dawnay, A., Farrington, K., Castledine, C., van Schalkwyk, D. & Warwick, G. UK Renal Registry 12th Annual Report (December 2009): chapter 10: biochemistry profile of patients receiving dialysis in the UK in 2008: national and centre-specific analyses. Nephron Clin. Pract. 115 (Suppl. 1), c187–c237 (2010).

    Article  CAS  Google Scholar 

  10. Fukuoka, K. et al. Glycated albumin levels predict long-term survival in diabetic patients undergoing haemodialysis. Nephrology 13, 278–283 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Georg Biesenbach.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Biesenbach, G., Pohanka, E. Glycated albumin or HbA1c in dialysis patients with diabetes?. Nat Rev Nephrol 7, 490–492 (2011). https://doi.org/10.1038/nrneph.2011.95

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrneph.2011.95

  • Springer Nature Limited

This article is cited by

Navigation