Skip to main content
Log in

Pathogens in decay

  • Genome Watch
  • Published:

From Nature Reviews Microbiology

View current issue Sign up to alerts

Abstract

Three bacterial genomes that have recently been published identify common evolutionary strategies among extremely disparate organisms. All of these species inhabit specialized niches in association with eukaryotic organisms, and all of them show evidence of the long-term genome decay that accompanies the acquisition of the restricted lifestyle of a pathogen or endosymbiont.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: These photographs of a flea (a) and two ticks (b) were taken during a 1972 study of disease carriers and pests found in and around migrant labour camps.
Figure 2

References

  1. McLeod, M. P. et al. Complete genome sequence of Rickettsia typhi and comparison with sequences of other rickettsiae. J. Bacteriol. 186, 5842–5855 (2004).

    Article  CAS  Google Scholar 

  2. Andersson, S. G. et al. The genome sequence of Rickettsia prowazekii and the origin of mitochondria. Nature 396, 133–140 (1998).

    Article  CAS  Google Scholar 

  3. Ogata, H. et al. Mechanisms of evolution in Rickettsia conorii and R. prowazekii. Science 293, 2093–2098 (2001).

    Article  CAS  Google Scholar 

  4. Horn, M. et al. Illuminating the evolutionary history of chlamydiae. Science 304, 728–730 (2004).

    Article  CAS  Google Scholar 

  5. Hartl, D. L. The origin of malaria: mixed messages from genetic diversity. Nature Rev. Microbiol. 1, 15–22 (2004).

    Article  Google Scholar 

  6. Monteiro-Vitorello, C. B. et al. The genome sequence of the Gram-positive sugar cane pathogen Leifsonia xyli subsp. xyli. Mol. Plant Microbe Interact. 17, 827–836 (2004).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Related links

Related links

DATABASES

Entrez

Chlamydia pneumoniae

Escherichia coli

Leifsonia xyli subsp. xyli CTCB07

Rickettsia conorii

Rickettsia prowazekii

Rickettsia typhi

Parachlamydia sp. UWE25

Xylella fastidiosa

FURTHER INFORMATION

The Pathogen Sequencing Unit

Rights and permissions

Reprints and permissions

About this article

Cite this article

Cerdeño-Tárraga, A., Thomson, N. & Parkhill, J. Pathogens in decay. Nat Rev Microbiol 2, 774–775 (2004). https://doi.org/10.1038/nrmicro1009

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrmicro1009

  • Springer Nature Limited

Navigation