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Hepatocellular carcinoma

Low risk of HCC in patients who have PSC and cirrhosis

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Primary sclerosing cholangitis (PSC) is understood to be associated with an increased risk of malignancy in the bile ducts, gallbladder and colon. The risk of hepatocellular carcinoma in the setting of PSC, however, is not well defined. Zenouzi et al. provide an analysis of their experience in a recent article

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Figure 1: Classic 'onion skin' fibrosis, causing obliteration of the bile ducts in primary sclerosing cholangitis.

References

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Authors and Affiliations

  1. Mayo Clinic, 200 First St. SW, Mayo Clinic, Rochester, 55901, MN, USA

    Andrea A. Gossard

  2. Arizona State University, 550 North 3rd Street, Phoenix, 85004, AZ, USA

    Keith D. Lindor

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  1. Andrea A. Gossard
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  2. Keith D. Lindor
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Correspondence to Keith D. Lindor.

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The authors declare no competing financial interests.

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Gossard, A., Lindor, K. Low risk of HCC in patients who have PSC and cirrhosis. Nat Rev Gastroenterol Hepatol 11, 276–277 (2014). https://doi.org/10.1038/nrgastro.2014.47

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