Pancreaticojejunostomy and pancreaticogastrostomy are both used for reconstruction after pancreaticoduodenectomy; which method is best is still debated. A nationwide multicentre randomized clinical trial that compared these two types of reconstruction has demonstrated that pancreaticogastrostomy is associated with a substantially lower rate of clinically relevant postoperative pancreatic fistula than pancreaticojejunostomy.
References
Fernández-Cruz, L. Pancreaticojejunostomy versus pancreaticogastrostomy. J. Hepatobiliary Pancreat. Sci. 18, 762–768 (2011).
Yeo, C. J. et al. A prospective randomized trial of pancreaticogastrostomy versus pancreaticojejunostomy after pancreaticoduodenectomy. Ann. Surg. 222, 580–588 (1995).
Bassi, C. et al. Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study. Ann. Surg. 242, 767–771 (2005).
Duffas, J. P. et al. A controlled randomized multicenter trial of pancreatogastrostomy or pancreatojejunostomy after pancreatoduodenectomy. Am. J. Surg. 189, 720–729 (2005).
Fernández-Cruz, L., Cosa, R., Blanco, L., López-Boado, M. A. & Astudillo, E. Pancreatogastrostomy with gastric partition after pylorus-preserving pancreatoduodenectomy versus conventional pancreatojejunostomy: a prospective randomized study. Ann. Surg. 248, 930–938 (2008).
Topal, B. et al. Pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy for pancreatic or periampullary tumours: a multicentre randomised trial. Lancet Oncol. 14, 655–662 (2013).
Bassi, C. et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery 138, 8–13 (2005).
Dindo, D., Demartines, N. & Clavien, P. A. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann. Surg. 240, 205–213 (2004).
Schmidt, C. M. et al. Effect of hospital volume, surgeon experience, and surgeon volume on patient outcomes after pancreaticoduodenectomy. A single-institution experience. Arch. Surg. 145, 634–640 (2010).
Pessaux, P. et al. Permeability and functionality of pancreaticogastrostomy after pancreaticoduodenectomy with dynamic magnetic resonance pancreatography after secretin stimulation. J. Am. Coll. Surg. 194, 454–462 (2002).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing financial interests.
Rights and permissions
About this article
Cite this article
Malleo, G., Bassi, C. Reconstruction methods after pancreaticoduodenectomy. Nat Rev Gastroenterol Hepatol 10, 445–446 (2013). https://doi.org/10.1038/nrgastro.2013.114
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrgastro.2013.114
- Springer Nature Limited
This article is cited by
-
Modified duct-to-mucosa versus conventional pancreaticoenterostomy for pancreaticoduodenectomy: a retrospective cohort study based on propensity score matching analysis
World Journal of Surgical Oncology (2019)
-
Polyester Preserves the Highest Breaking Point After Prolonged Incubation in Pancreatic Juice
Journal of Gastrointestinal Surgery (2018)