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Fracture risk in the JUPITER trial—statin treatment or not?

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Observational studies suggest that statin treatment has a fracture-preventive effect; however, there is only limited supporting evidence from randomized controlled trials. Now, results from the JUPITER trial show that rosuvastatin treatment does not reduce the risk of fractures and, further, that levels of high sensitivity C-reactive protein are not associated with fracture risk.

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Correspondence to Peter Vestergaard.

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Vestergaard, P. Fracture risk in the JUPITER trial—statin treatment or not?. Nat Rev Endocrinol 11, 135–136 (2015). https://doi.org/10.1038/nrendo.2014.232

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