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Primary aldosteronism in 2011

Towards a better understanding of causation and consequences

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From Nature Reviews Endocrinology

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With primary aldosteronism now widely acknowledged as common and associated with both hypertension-related and non-hypertension-related pathology, research interest into its causes and consequences continues to grow. In 2011, major breakthroughs occurred in understanding the role and nature of underlying genetic disturbances and elucidating the pathophysiology of its cardiovascular sequelae.

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Figure 1: Cellular and functional zones of steroid synthesis in the adrenal cortex.

References

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Authors and Affiliations

  1. Endocrine Hypertension Research Center, University of Queensland School of Medicine, Greenslopes and Princess Alexandra Hospitals, Ipswich Road, Woolloongabba, 4102, Brisbane, Australia

    Michael Stowasser

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  1. Michael Stowasser
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Stowasser, M. Towards a better understanding of causation and consequences. Nat Rev Endocrinol 8, 70–72 (2012). https://doi.org/10.1038/nrendo.2011.223

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