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Low-dose flutamide for hirsutism: into the limelight, at last

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Evidence indicates that flutamide, a specific and potent androgen-receptor blocker, when given in low dose (∼1 mg/kg daily), confers a first-choice balance between antiandrogenic efficacy and hepatic safety for women and adolescent girls with hirsutism or other androgen-related symptoms.

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References

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Authors and Affiliations

  1. Department of Woman and Child, University of Leuven, Leuven, 3000, Belgium

    Francis de Zegher

  2. Pediatric & Adolescent Endocrinology, Hospital Sant Joan de Deu, University of Barcelona, Barcelona, 08950, Spain

    Lourdes Ibáñez

Authors
  1. Francis de Zegher
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  2. Lourdes Ibáñez
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Correspondence to Lourdes Ibáñez.

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The authors declare no competing financial interests.

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de Zegher, F., Ibáñez, L. Low-dose flutamide for hirsutism: into the limelight, at last. Nat Rev Endocrinol 6, 421–422 (2010). https://doi.org/10.1038/nrendo.2010.119

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