Clinical success with Trevena's 'biased' G protein-coupled receptor ligand highlights the potential of exploring the nuances of receptor pharmacology.
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Kingwell, K. Pioneering biased ligand offers efficacy with reduced on-target toxicity. Nat Rev Drug Discov 14, 809–810 (2015). https://doi.org/10.1038/nrd4784
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DOI: https://doi.org/10.1038/nrd4784
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