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Neurodevelopmental disorders

Glutamate blockers show benefit in models of autism spectrum disorders

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ORIGINAL RESEARCH PAPERS

  1. Michalon, A. et al. Chronic pharmacological mGlu5 inhibition corrects fragile X in adult mice. Neuron 74, 49–56 (2012)Article

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  2. Silverman, J. L. et al. Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism. Sci. Transl. Med. 4, 131ra51 (2012)Article

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Authors
  1. Charlotte Harrison
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Harrison, C. Glutamate blockers show benefit in models of autism spectrum disorders. Nat Rev Drug Discov 11, 440–441 (2012). https://doi.org/10.1038/nrd3761

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