Skip to main content

Advertisement

Log in

Accelerating the pulse of cardiovascular R&D

  • Comment
  • Published:

From Nature Reviews Drug Discovery

View current issue Sign up to alerts

Abstract

Renewed commitment to cardiovascular drug development is needed to combat what is likely to be the leading cause of death for the next two decades. How might this be achieved?

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Garber, A. M. An uncertain future for cardiovascular drug development? N. Engl. J. Med. 360, 12 (2009).

    Article  Google Scholar 

  2. World Health Organization. Cardiovascular diseases (CVDs), [online] (2009)

  3. Yang, W. et al. Prevalence of diabetes among men and women in China. N. Engl. J. Med. 362, 1090–1101 (2010).

    Article  CAS  Google Scholar 

  4. FDA approves updated warfarin (Coumadin) prescribing information. [online], (2007).

  5. Teslovich, T. M. et al. Biological, clinical and population relevance of 95 loci for blood lipids. Nature 466, 707–713 (2010).

    Article  CAS  Google Scholar 

  6. Calhoun, D. A. et al. Resistant hypertension: diagnosis, evaluation, treatment: a scientific statement from the American Heart Association Professional Education Committee of the Council for High Blood Pressure Research. Hypertension 51, 1403–1419 (2008).

    Article  CAS  Google Scholar 

  7. Amar, L. et al. Aldosterone synthase inhibition with LCI699. A proof-of-concept study in patients with primary aldosteronism. Hypertension 13 Sep 2010 (doi: 10.1161/HYPERTENSIONAHA.110.157271).

  8. Connolly, S. J. et al. Dabigatran versus warfarin in patients with atrial fibrillation. N. Engl. J. Med. 361, 1139–1151 (2009).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Ethics declarations

Competing interests

A.P. is employed by Merck and Co., Inc. Whitehouse Station, New Jersey, USA.

Supplementary information

Supplementary information Figure S1

50 years of advances in cardiovascular disease therapies. (PDF 260 kb)

Supplementary information Figure S2

Alliances by therapeutic category. (PDF 191 kb)

Rights and permissions

Reprints and permissions

About this article

Cite this article

Plump, A. Accelerating the pulse of cardiovascular R&D. Nat Rev Drug Discov 9, 823–824 (2010). https://doi.org/10.1038/nrd3315

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nrd3315

  • Springer Nature Limited

This article is cited by

Navigation