References
World Health Organization. Epilepsy: key facts. WHO website [online], (2009).
Cereghino, J. J. et al. Levetiracetam for partial seizures: results of a double-blind, randomized clinical trial. Neurology 55, 236–242 (2000).
Beran, R. G. et al. Efficacy and safety of levetiracetam 1000–3000mg/day in patients with refractory partial-onset seizures: a multicenter, open-label single-arm study. Epilepsy Res. 63, 1–9 (2005).
Morrell, M. J. et al. The KEEPER trial: levetiracetam adjunctive treatment of partial-onset seizures in an open-label community-based study. Epilepsy Res. 56, 209–120 (2003).
Sridharan, R. Epidemiology of epilepsy. Curr. Sci. 82, 664–670 (2002).
Datamonitor. Pipeline and commercial insight: neuropathic pain — evaluation of the current and future market dynamics, DMHC2403 (October 2008).
Pfizer. Press release 21 Jun 2007: Pfizer's Lyrica receives FDA approval for fibromyalgia based on expedited review. Pfizer website [online], (2007).
Datamonitor. Commercial and pipeline insight: fibromyalgia — approvals legitimize condition and expose underserved patient population, DMHC2405 (July 2008).
Takeshima, T. et al. Population-based door-to-door survey of migraine in Japan: the Daisen study. Headache 44, 8–19 (2004).
Sanchez-Perez, R. et al. A descriptive study of migraine in a rural population of Area del Comtat. Rev. Neurol. 28, 373–376 (1999).
Silberstein, S. D., Neto, W., Schmitt, J. & Jacobs, D. for the MIGR-001 Study Group. Topiramate in migraine prevention: results of a large, controlled trial. Arch. Neurology 61, 490–495 (2004).
MIDAS sales data and Prescribing Insight. (IMS Health, 2009).
Datamonitor. Commercial insight: anticonvulsants — non-epilepsy indication expansions provide blockbuster potential, DMHC2544 (October 2009).
Author information
Authors and Affiliations
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Mackey, C. The anticonvulsants market. Nat Rev Drug Discov 9, 265–266 (2010). https://doi.org/10.1038/nrd3076
Issue Date:
DOI: https://doi.org/10.1038/nrd3076
- Springer Nature Limited
This article is cited by
-
Ambiguous bromine
Nature Chemistry (2012)
-
Natural products as potential anticonvulsants: Caffeoylquinic acids
Archives of Pharmacal Research (2012)
-
Erratum: The anticonvulsants market
Nature Reviews Drug Discovery (2010)