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Lung cancer

First-line immunotherapy in lung cancer — taking the first step

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The use of programmed cell-death protein 1 (PD-1) inhibitors has become the standard-of-care approach for patients with advanced-stage, previously treated non-small-cell lung cancer. The inevitable adoption of these agents in the first-line setting is rapidly approaching, but the optimal strategy remains unclear. Two published clinical trial reports, examining different approaches, help to frame this question.

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Authors and Affiliations

  1. Stephen V. Liu and Giuseppe Giaccone are at the Lombardi Comprehensive Cancer Center, Georgetown University, 2970 Reservoir Road NW, Washington District of Columbia 20007, USA.,

    Stephen V. Liu & Giuseppe Giaccone

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  1. Stephen V. Liu
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  2. Giuseppe Giaccone
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Correspondence to Giuseppe Giaccone.

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The authors declare no competing financial interests.

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Liu, S., Giaccone, G. First-line immunotherapy in lung cancer — taking the first step. Nat Rev Clin Oncol 13, 595–596 (2016). https://doi.org/10.1038/nrclinonc.2016.148

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