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Urological cancer

Aspirin and the risk of prostate cancer mortality

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From Nature Reviews Clinical Oncology

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The observational registry CaPSURE study reported that men with prostate cancer who were taking aspirin were less likely to die of prostate cancer than nonusers. This favourable effect seems to be stronger than that observed in a pooled analysis of randomized clinical trials of aspirin, and in other observational studies.

Key Points

  • In a follow-up study of patients with prostate cancer, aspirin was related to an appreciable decrease in prostate cancer mortality

  • This decrease has been related to a favourable action of aspirin on thrombosis

  • Observational studies suggest a modest decrease in prostate cancer risk among aspirin users

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Authors and Affiliations

  1. Department of Epidemiology, “Mario Negri” Institute for Pharmacologic Research, Via La Masa 19, Milan, 20156, Italy

    Carlo La Vecchia & Cristina Bosetti

  2. Department of Clinical Sciences and Community Health, University of Milan, Via Venezian 1, Milan, 20133, Italy

    Carlo La Vecchia

Authors
  1. Carlo La Vecchia
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  2. Cristina Bosetti
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Corresponding author

Correspondence to Carlo La Vecchia.

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The authors declare no competing financial interests.

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La Vecchia, C., Bosetti, C. Aspirin and the risk of prostate cancer mortality. Nat Rev Clin Oncol 9, 616–617 (2012). https://doi.org/10.1038/nrclinonc.2012.182

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  • DOI: https://doi.org/10.1038/nrclinonc.2012.182

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