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Pharmacotherapy

Intracoronary streptokinase in acute myocardial infarction

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Despite angiographically successful primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction, microcirculatory failure is common and leads to an increased risk of morbidity and mortality. The administration of intracoronary streptokinase immediately after PCI may improve outcomes and provides a promising potential therapy for the future.

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Armstrong, P. Intracoronary streptokinase in acute myocardial infarction. Nat Rev Cardiol 7, 67–69 (2010). https://doi.org/10.1038/nrcardio.2009.230

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