Abstract
Most of our current knowledge of melanoma is derived from the study of patients from populations of European descent, for whom public health, sun protection initiatives and screening measures have appreciably decreased disease mortality. Notably, some melanoma subtypes that most commonly develop in other populations are not associated with exposure to ultraviolet (UV) light, suggesting a different disease aetiology. Further study of these subtypes is necessary to understand their risk factors and genomic architecture, and to tailor therapies and public health campaigns to benefit patients of all ethnic groups.
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Acknowledgements
The authors thank R. van Doorn, V. V. Iyer and M. del C. Ávila-Arcos for helpful comments.
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Supplementary information S1 (figure)
Distribution of common melanoma subtypes across different countries (PDF 715 kb)
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Ossio, R., Roldán-Marín, R., Martínez-Said, H. et al. Melanoma: a global perspective. Nat Rev Cancer 17, 393–394 (2017). https://doi.org/10.1038/nrc.2017.43
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DOI: https://doi.org/10.1038/nrc.2017.43
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